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Educational Articles

Dogs + Medications & Supplements

  • Isoxsuprine is a vasodilator that relaxes blood vessel walls outside of major organs. It has been used to help treat frostbite in birds and in certain conditions in dogs. It is used “off label” or “extra label” in animals. Isoxsuprine comes in tablet and powder forms. Avoid use in animals who have recently given birth or have bleeding.

  • Itraconazole is given by mouth in the form of a capsule, tablet, or liquid to treat fungal infections in cats and for off label treatment in dogs and small mammals. The most common side effects are anorexia, vomiting, liver toxicity, skin lesions, or limb and vessel swelling. It should not be used in pets with liver disease or low stomach acid production, and used with caution in pregnant, lactating, or pets with heart disease. If a negative reaction occurs, call your veterinary office.

  • Ivermectin is most commonly used as a heartworm preventive in dogs and cats. It also used off label for treating a variety of internal and external parasites. Ivermectin may be combined with other deworming medications. Ivermectin is available as tablets, chewable tablets, a topical liquid (for ear mite treatments), and an injectable that your veterinarian will administer. Some breeds of dogs (e.g., collies, sheepdogs, and collie- or sheepdog-cross breeds) are more sensitive to ivermectin than others. There are some medications that interact with ivermectin, so it is important to tell your veterinarian about all medications your pet is taking. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Ivermectin + pyrantel is a heartworm disease preventive that treats and controls hookworms and roundworms in dogs. Ivermectin + pyrantel is given by mouth as a flavored chew tablet. At prescribed doses, ivermectin + pyrantel is well-tolerated. Some dog breeds (e.g., collies, sheepdogs, and collie- or sheepdog-cross breeds) are more sensitive to ivermectin than others; your veterinarian will advise you on the safety of using this medication in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Ivermectin + pyrantel + praziquantel is a combination of anti-parasitic medications used to prevent heartworms and control roundworm, hookworm, and tapeworm in dogs. It is given by mouth as a flavored chew tablet. At prescribed doses, this product is generally well-tolerated but some dogs may experience decreased appetite, vomiting, diarrhea, or burping. Certain drugs may interact with those in this combination product; it is extremely important to let your veterinarian know about any medications or supplements that your pet is taking. If your dog has an adverse reaction to this product, call your veterinary office immediately.

  • Kaolin/pectin is given by mouth and is used off label to treat diarrhea and certain toxicities. Use as directed by your veterinarian. Side effects are uncommon, but constipation is possible (rarely). Do not use in pets that are allergic to it, or to control severe diarrhea or diarrhea that is caused by an infection. Do not use the combination product that includes bismuth subsalicylate in cats. If a negative reaction occurs, please call your veterinary office.

  • Ketoconazole is an antifungal given by mouth in the form of a tablet, used off label to treat fungal infections in dogs, cats, small mammals, and reptiles. The most common side effects are vomiting, diarrhea, lack of appetite, and weight loss. Do not use in pets that are allergic to it, and use severe caution when using in cats or pregnant pets. If a negative reaction occurs, please call your veterinary office.

  • Ketoprofen is given by mouth in the form of a capsule or tablet to treat pain and inflammation in dogs and horses. It’s use in animals is off label. Do not use this medication in pets that are allergic to it, or in pets concurrently using corticosteroids or other NSAIDs. If a negative reaction occurs, call your veterinary office.

  • Ketorolac is applied topically to the eye to treat pain and inflammation of the eye. Its use in dogs and cats is off label. Do not use this medication in pets that are allergic to it. If a negative reaction occurs, call your veterinary office.

  • Lactulose is used off label and is given by mouth to treat high blood ammonia levels and constipation. The most common side effects are diarrhea, bloating, gas, and abdominal cramping. Do not use in pets that are allergic to it or in pets with intestinal blockage/obstruction. If a negative reaction occurs, please call your veterinary office.