Educational Articles
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Rifampin is commonly used off label to treat infections in horses, and occasionally in dogs and cats. It is usually given by mouth in the form of a capsule or compounded liquid. The most common side effects are vomiting, diarrhea, or reduced appetite. Liver dysfunction is possible. A change in the color of urine, tears, and saliva to a red/orange color is expected but may stain fabrics. Use with caution in pets that have pre-existing liver disease, are pregnant, are elderly, or are lactating. If a negative reaction occurs, call your veterinary office.
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Robenacoxib (brand name: Onsior) is given by mouth in the form of a tablet to treat pain and inflammation associated with surgery or other musculoskeletal conditions in dogs and cats. Do not use this medication in pets that are allergic to it, or in pets concurrently using corticosteroids or other NSAIDs. If a negative reaction occurs, call your veterinary office.
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Ronidazole is given by mouth and is used off label to treat Tritrichomonas foetus, trichomonas, and giardia in dogs, cats, and birds. It should not be used in farmed animals. Common side effects include vomiting and decreased appetite. Do not use in pets that are allergic to it or other nitroimidazoles such as metronidazole. If a negative reaction occurs, please call your veterinary office.
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SAMe is given by mouth and is used on label and over the counter to treat liver disease and other conditions. Give as directed by your veterinarian. Side effects are uncommon but may include mild stomach upset. Antidepressants, dextromethorphan, meperidine, pentazocine, and tramadol should be used with caution when given with SAMe. Inform your veterinarian of all medications, vitamins, and supplements that your pet is taking. If a negative reaction occurs, please call your veterinary office.
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SAMe or S-adenosyl-methionine + Silybin (brand name: Denamarin®) is a combination supplement commonly used to support liver health in cats and dogs. The body uses SAMe for many important functions, such as brain, heart, hormone, antioxidant, detoxifying, and other metabolic functions. The combination of SAMe and Silybin is used to support liver and brain health. This article discusses side effects, interactions, monitoring, and storage.
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Do you have medications stored in the bathroom cabinet, kitchen drawer, and pantry shelf? Are random bottles haphazardly tossed into the “pharmacy”? Medications are meant to help us and our pets, but they can do more harm than good if stored or administered incorrectly. You can protect your family and pets by safely handling and disposing of medications.
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Selemectin is used topically on the skin to treat various parasites, both on and off label. Side effects are rare but may include hair loss at application site, gastrointestinal upset, skin reactions, or neurologic signs. Use with caution in sick or underweight pets, or dogs with the MDR1 mutation. If a negative reaction occurs, please call your veterinary office.
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Selamectin + sarolaner is used topically on the skin to treat various parasites, both on and off-label, and prevent heartworm in cats. Side effects are rare but may include hair loss at the application site, gastrointestinal upset, skin reactions, or neurologic signs. It should be used with caution in sick or underweight cats. If a negative reaction occurs, please call your veterinary office.
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Selegiline is typically given by mouth and is used off and on label to treat signs due to cognitive dysfunction syndrome, pituitary dependent Cushing’s disease, anxiety and certain phobias. Side effects may include vomiting, diarrhea, drooling, lack of appetite, and behavioral changes. Do not use in pets that are allergic to it, are aggressive, or in pets receiving other MAOIs, including certain tick collars. If a negative reaction occurs, please call your veterinary office.
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Sertraline is given by mouth and is used off label to treat behavior disorders in dogs and cats. Common side effects include tiredness, vomiting, diarrhea, lack of appetite, anxiety, irritability, sleeplessness, shaking, tremors, itchy skin, or panting. Do not use in pets that are allergic to it or other SSRIs, or pets that are using MAOIs, flea/tick collars, or cisapride. If a negative reaction occurs, please call your veterinary office.